Aetiology and Biomarkers of Canine Ccl Disease
نویسنده
چکیده
Disease of the cranial cruciate ligament (CCL) is the most common condition to affect the canine stifle joint. The postulated factors involved in the pathogenesis of CCL rupture are many and include: genetics, breed, age, gender, neutering, ischaemia, obesity, immune mechanisms, tibial plateau angle, intercondylar notch, and local biomechanics. Some of these factors have been investigated, and some are currently under investigation. These investigations may lead to biomarkers for risk, diagnosis or disease progression. Such biomarkers may be based on molecular genetics, disease-associated proteins, or imaging.
منابع مشابه
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